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"Firm banks on stem cells" posted by ~Ray
Posted on 2008-11-27 14:17:45

It’s being pitched as a forward thinking approach to curing cancers and other diseases. But the price tag is high it’s not covered by insurance and there’s no guarantee it’ll bring home the bacon in the desire run. A New York biotechnology affiliate is the first firm in the Las Vegas Valley to give a way for people to deposit and preserve s “It’s a concept that if proven viable will provide people with some alternative therapies,” vice president of administration at said about the storage of stem cells for future medical treatment. “There are lots of anecdotal cases showing significant improvements as a result of using adult stem cells to treat diseases.” This entry was posted on Friday. November 2nd. 2007 at 2:57 pmand is filed under. You can follow any responses to this entry through the feed. You can or from your own site. This communicate is funded in move by a give from the US Small Business Administration (SBA). SBA’s funding should not be construed as an endorsement of any products opinions or services. All SBA-funded projects are extended to the public on a non discriminatory basis. Reasonable accommodations for persons with disabilities ordain be made if requested at least two weeks in advance. Contact Emily Somerville at or (775) 853-4226.

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"Study looks at interest level of healthy, young adults in ..." posted by ~Ray
Posted on 2008-10-10 03:17:06

The test being used is designed to yield information about 15 different genes that play roles in type 2 diabetes coronary heart disease high blood cholesterol high blood pressure osteoporosis lung cancer colorectal cancer and malignant melanoma. “The Multiplex Initiative will provide insights that will be key to advancing the concept of personalized medicine,” said NHGRI Scientific Director Eric Green. M. D.. Ph. D. “As genomic technologies are introduced for wider use researchers and clinicians will need to know how genetic susceptibility tests will be received by patients. This study will be an important first step in understanding how such testing can be practically used in primary care settings.” Researchers at Henry Ford Health System a major health provider in metropolitan Detroit are recruiting individuals between the ages of 25 and 40 to volunteer to participate in the study. The participants are being selected through patient lists from Health Alliance Plan the largest managed care plan in Michigan owned by Henry Ford Health System and the Henry Ford Medical Group the health system’s group medical practice of more than 900 physicians and scientists. A total of 1,000 participants who meet the study’s eligibility requirements will be offered free multiplex genetic testing. Multiplex tests such as the one being used in this study can detect common variants of genes that slightly alter the chances of acquiring particular diseases. The term “multiplex” refers to performing multiple genetic tests using the same blood sample. On average those who get tested in the Multiplex Initiative will receive results indicating that they carry four to 10 risk versions of individual genes. However having a risk version of one of the 15 genes on the multiplex genetic test does not mean that a person is certain to get the condition only that he or she might have a greater chance of developing the disorder. Researchers also note that many things other than genetics contribute to the risk of common diseases and that for most people lifestyle factors such as diet exercise smoking and sun exposure are major contributors to developing common diseases. “The Multiplex Initiative will give us an unprecedented opportunity to learn about the public’s receptivity to genetic susceptibility testing and give insights into the added role this testing might play in improving health,” said lead investigator Colleen McBride. Ph. D. senior investigator and chief of NHGRI’s Social and Behavioral Research Branch. “We are looking at a prototype of multiplex testing in a research context first to see if we can effectively communicate what these tests mean for health risks and begin to evaluate how these tests might be used to inspire healthy people to stay healthy.” In addition to McBride and Lawrence Brody. Ph. D. a senior investigator in the NHGRI Genome Technology Branch the team includes researchers from the Henry Ford Health System in Detroit and the Group Health Cooperative in Seattle. Epidemiologist Sharon Hensley Alford. M. P. H of Henry Ford Health System is leading the Detroit-based team while the Seattle group is headed by Eric B. Larson. M. D.. M. P. H. executive director of the Group Health Center for Health Studies and Robert Reid. M. D.. Ph. D.. Group Health Cooperative’s associate medical director for preventive care. The Seattle group organized the survey developed survey instruments and are administering the baseline phone interviews to recruit subjects. One of the important aspects of this study is the evaluation of participants’ responses to the offer of free genetic testing in order to learn more about who is and is not interested in such tests what influences decisions about whether to be tested and how individuals who are tested interact with the health care system. An innovative system for data collection and analysis has been designed for the project by the NHGRI Bioinformatics and Scientific Programming Core led by NHGRI’s Deputy Scientific Director Andy Baxevanis. Ph. D. The genetic testing will be conducted at the Center for Inherited Disease Research (CIDR) a world-class genotyping facility that is jointly operated by NIH and The Johns Hopkins University. Once enrolled participants will be asked to review information online about the multiplex genetic test and to decide whether they are interested in taking the test. Those who agree to testing will meet with a research educator who will provide more information about the risks and benefits of testing and will obtain the patient’s written consent. Blood samples from individuals in this group will be analyzed at the CIDR laboratory which has Clinical Laboratory Improvement Amendments (CLIA) certification. Test results will be mailed to participants. Follow-up telephone calls will then be made by trained research educators to help participants interpret and understand their results. The study will also include follow-up interviews with participants three months after receiving their results. Participants will continue to receive newsletters for two years to update them on new developments about the tested genes. To protect patient privacy test results obtained during the Multiplex study will not automatically become a part of participants’ medical records. However participants who want to share their test results with their health care providers may do so. According to Dr. McBride the Multiplex Initiative will inform health care professionals about how to communicate genetic risk to patient populations and will establish an infrastructure for additional research studies aiming to answer social and behavioral questions important for the genome era. Studies such as this one are a first step toward translating genetic research into health care.

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"Study looks at interest level of healthy, young adults in ..." posted by ~Ray
Posted on 2008-10-10 03:16:44

The test being used is designed to yield information about 15 different genes that play roles in type 2 diabetes coronary heart disease high blood cholesterol high blood pressure osteoporosis lung cancer colorectal cancer and malignant melanoma. “The Multiplex Initiative will provide insights that will be key to advancing the concept of personalized medicine,” said NHGRI Scientific Director Eric Green. M. D.. Ph. D. “As genomic technologies are introduced for wider use researchers and clinicians will need to know how genetic susceptibility tests will be received by patients. This study will be an important first step in understanding how such testing can be practically used in primary care settings.” Researchers at Henry Ford Health System a major health provider in metropolitan Detroit are recruiting individuals between the ages of 25 and 40 to volunteer to participate in the study. The participants are being selected through patient lists from Health Alliance Plan the largest managed care plan in Michigan owned by Henry Ford Health System and the Henry Ford Medical Group the health system’s group medical practice of more than 900 physicians and scientists. A total of 1,000 participants who meet the study’s eligibility requirements will be offered free multiplex genetic testing. Multiplex tests such as the one being used in this study can detect common variants of genes that slightly alter the chances of acquiring particular diseases. The term “multiplex” refers to performing multiple genetic tests using the same blood sample. On average those who get tested in the Multiplex Initiative will receive results indicating that they carry four to 10 risk versions of individual genes. However having a risk version of one of the 15 genes on the multiplex genetic test does not mean that a person is certain to get the condition only that he or she might have a greater chance of developing the disorder. Researchers also note that many things other than genetics contribute to the risk of common diseases and that for most people lifestyle factors such as diet exercise smoking and sun exposure are major contributors to developing common diseases. “The Multiplex Initiative will give us an unprecedented opportunity to learn about the public’s receptivity to genetic susceptibility testing and give insights into the added role this testing might play in improving health,” said lead investigator Colleen McBride. Ph. D. senior investigator and chief of NHGRI’s Social and Behavioral Research Branch. “We are looking at a prototype of multiplex testing in a research context first to see if we can effectively communicate what these tests mean for health risks and begin to evaluate how these tests might be used to inspire healthy people to stay healthy.” In addition to McBride and Lawrence Brody. Ph. D. a senior investigator in the NHGRI Genome Technology Branch the team includes researchers from the Henry Ford Health System in Detroit and the Group Health Cooperative in Seattle. Epidemiologist Sharon Hensley Alford. M. P. H of Henry Ford Health System is leading the Detroit-based team while the Seattle group is headed by Eric B. Larson. M. D.. M. P. H. executive director of the Group Health Center for Health Studies and Robert Reid. M. D.. Ph. D.. Group Health Cooperative’s associate medical director for preventive care. The Seattle group organized the survey developed survey instruments and are administering the baseline phone interviews to recruit subjects. One of the important aspects of this study is the evaluation of participants’ responses to the offer of free genetic testing in order to learn more about who is and is not interested in such tests what influences decisions about whether to be tested and how individuals who are tested interact with the health care system. An innovative system for data collection and analysis has been designed for the project by the NHGRI Bioinformatics and Scientific Programming Core led by NHGRI’s Deputy Scientific Director Andy Baxevanis. Ph. D. The genetic testing will be conducted at the Center for Inherited Disease Research (CIDR) a world-class genotyping facility that is jointly operated by NIH and The Johns Hopkins University. Once enrolled participants will be asked to review information online about the multiplex genetic test and to decide whether they are interested in taking the test. Those who agree to testing will meet with a research educator who will provide more information about the risks and benefits of testing and will obtain the patient’s written consent. Blood samples from individuals in this group will be analyzed at the CIDR laboratory which has Clinical Laboratory Improvement Amendments (CLIA) certification. Test results will be mailed to participants. Follow-up telephone calls will then be made by trained research educators to help participants interpret and understand their results. The study will also include follow-up interviews with participants three months after receiving their results. Participants will continue to receive newsletters for two years to update them on new developments about the tested genes. To protect patient privacy test results obtained during the Multiplex study will not automatically become a part of participants’ medical records. However participants who want to share their test results with their health care providers may do so. According to Dr. McBride the Multiplex Initiative will inform health care professionals about how to communicate genetic risk to patient populations and will establish an infrastructure for additional research studies aiming to answer social and behavioral questions important for the genome era. Studies such as this one are a first step toward translating genetic research into health care.

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"Study looks at interest level of healthy, young adults in ..." posted by ~Ray
Posted on 2008-10-10 03:16:32

The test being used is designed to yield information about 15 different genes that play roles in type 2 diabetes coronary heart disease high blood cholesterol high blood pressure osteoporosis lung cancer colorectal cancer and malignant melanoma. “The Multiplex Initiative will provide insights that will be key to advancing the concept of personalized medicine,” said NHGRI Scientific Director Eric Green. M. D.. Ph. D. “As genomic technologies are introduced for wider use researchers and clinicians will need to know how genetic susceptibility tests will be received by patients. This study will be an important first step in understanding how such testing can be practically used in primary care settings.” Researchers at Henry Ford Health System a major health provider in metropolitan Detroit are recruiting individuals between the ages of 25 and 40 to volunteer to participate in the study. The participants are being selected through patient lists from Health Alliance Plan the largest managed care plan in Michigan owned by Henry Ford Health System and the Henry Ford Medical Group the health system’s group medical practice of more than 900 physicians and scientists. A total of 1,000 participants who meet the study’s eligibility requirements will be offered free multiplex genetic testing. Multiplex tests such as the one being used in this study can detect common variants of genes that slightly alter the chances of acquiring particular diseases. The term “multiplex” refers to performing multiple genetic tests using the same blood sample. On average those who get tested in the Multiplex Initiative will receive results indicating that they carry four to 10 risk versions of individual genes. However having a risk version of one of the 15 genes on the multiplex genetic test does not mean that a person is certain to get the condition only that he or she might have a greater chance of developing the disorder. Researchers also note that many things other than genetics contribute to the risk of common diseases and that for most people lifestyle factors such as diet exercise smoking and sun exposure are major contributors to developing common diseases. “The Multiplex Initiative will give us an unprecedented opportunity to learn about the public’s receptivity to genetic susceptibility testing and give insights into the added role this testing might play in improving health,” said lead investigator Colleen McBride. Ph. D. senior investigator and chief of NHGRI’s Social and Behavioral Research Branch. “We are looking at a prototype of multiplex testing in a research context first to see if we can effectively communicate what these tests mean for health risks and begin to evaluate how these tests might be used to inspire healthy people to stay healthy.” In addition to McBride and Lawrence Brody. Ph. D. a senior investigator in the NHGRI Genome Technology Branch the team includes researchers from the Henry Ford Health System in Detroit and the Group Health Cooperative in Seattle. Epidemiologist Sharon Hensley Alford. M. P. H of Henry Ford Health System is leading the Detroit-based team while the Seattle group is headed by Eric B. Larson. M. D.. M. P. H. executive director of the Group Health Center for Health Studies and Robert Reid. M. D.. Ph. D.. Group Health Cooperative’s associate medical director for preventive care. The Seattle group organized the survey developed survey instruments and are administering the baseline phone interviews to recruit subjects. One of the important aspects of this study is the evaluation of participants’ responses to the offer of free genetic testing in order to learn more about who is and is not interested in such tests what influences decisions about whether to be tested and how individuals who are tested interact with the health care system. An innovative system for data collection and analysis has been designed for the project by the NHGRI Bioinformatics and Scientific Programming Core led by NHGRI’s Deputy Scientific Director Andy Baxevanis. Ph. D. The genetic testing will be conducted at the Center for Inherited Disease Research (CIDR) a world-class genotyping facility that is jointly operated by NIH and The Johns Hopkins University. Once enrolled participants will be asked to review information online about the multiplex genetic test and to decide whether they are interested in taking the test. Those who agree to testing will meet with a research educator who will provide more information about the risks and benefits of testing and will obtain the patient’s written consent. Blood samples from individuals in this group will be analyzed at the CIDR laboratory which has Clinical Laboratory Improvement Amendments (CLIA) certification. Test results will be mailed to participants. Follow-up telephone calls will then be made by trained research educators to help participants interpret and understand their results. The study will also include follow-up interviews with participants three months after receiving their results. Participants will continue to receive newsletters for two years to update them on new developments about the tested genes. To protect patient privacy test results obtained during the Multiplex study will not automatically become a part of participants’ medical records. However participants who want to share their test results with their health care providers may do so. According to Dr. McBride the Multiplex Initiative will inform health care professionals about how to communicate genetic risk to patient populations and will establish an infrastructure for additional research studies aiming to answer social and behavioral questions important for the genome era. Studies such as this one are a first step toward translating genetic research into health care.

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"Mutant gene that starves the brain of serotonin 10 times more ..." posted by ~Ray
Posted on 2008-03-26 01:33:24

A mutant gene that starves the brain of serotonin a mood-regulating chemical messenger has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects inform researchers funded by the National Institutes of Health’s National initiate of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI). Patients with the mutation failed to respond come up to the most commonly prescribed class of antidepressant medications which work via serotonin suggesting that the mutation may underlie a treatment-resistant subtype of the illness. The mutant gene codes for the hit enzyme tryptophan hydroxylase-2 that makes serotonin and results in 80 percent less of the neurotransmitter. It was carried by nine of 87 depressed patients three of 219 healthy controls and none of 60 bipolar disturb patients. Drs. Marc Caron. Xiaodong Zhang and colleagues at Duke Unversity announced their findings in the January 2005 Neuron published online in mid-December. “If confirmed this discovery could bring about to a genetic test for vulnerability to depression and a way to predict which patients might respond best to serotonin-selective antidepressants,” noted NIMH Director Thomas Insel. M. D. The Duke researchers had previously reported in the July 9. 2004 Science that some mice undergo a tiny one-letter variation in the grade of their tryptophan hydroxylase gene (Tph2) that results in 50-70 percent less serotonin. This suggested that such a variant gene might also exist in humans and might be involved in mood and anxiety disorders which often act to serotonin selective reuptake inhibitors (SSRIs) - antidepressants that block the re-absorption of serotonin enhancing its availability to neurons. In the current chew over a similar variant culled from human subjects produced 80 percent less serotonin in cell cultures than the common version of the enzyme. More than 10 percent of the 87 patients with unipolar major depression carried the mutation compared to only one percent of the 219 controls. Among the nine SSRI-resistant patient carriers seven had a family history of mental illness or substance do by six had been suicidal and four had generalized anxiety. Although they fell bunco of meeting criteria for major depression the three hold back group carriers also had family histories of psychiatric problems and experienced mild depression and anxiety symptoms. This points up the complexity of these disorders say the researchers. For example study depression is thought to be 40-70 percent heritable but likely involves an interaction of several genes with environmental events. Previous studies have linked depression with the same region of chromosome 12 where the tryptophan hydroxylase-2 gene is located. Whether the absence of the mutation among 60 patients with bipolar disorder proves to be evidence of a different underlying biology remains to be investigated in future studies. The researchers say their finding provides a potential molecular mechanism for aberrant serotonin answer in neuropsychiatric disorders. Also participating in the study were: Raul Gainetdinov. Jean-Marin Beaulieu. Tatyana Sotnikova. Lauranell Burch. Redford Williams. David Schwartz and Ranga Krishnan. Duke University. In addition to grants from NIMH and NHLBI the chew over was also funded by the Human Frontiers Science schedule and the Canadian Institute of Health Research.

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"NIEHS - National Institute of Environmental Health Sciences - News" posted by ~Ray
Posted on 2007-12-15 17:41:34

NIEHS - National initiate of Environmental Health Sciences - News News of recent activities of the National Institute of Environmental Health Sciences (NIEHS) Source: www niehs nih gov NIBIB Invests in Quantum investigate - October 4. 2007 The National initiate of Biomedical Imaging and Bioengineering (NIBIB) move of the National Institutes of Health (NIH) today announced the allocate of more than $12 million in grants to support investigate and development of potentially high-impact innovative technologies to advance health compassionate. obtain: www nih gov Scientists grade Genome of Intestinal Parasite that Afflicts Hikers and Kids in Daycare - September 27. 2007 Giardia lamblia is a strange-looking parasite that swims in the gut spreads through entice persists in contaminated wet and is responsible for more than 20,000 reported infections a year in the United States. Now it has finally spilled its genetic secrets. obtain: www nih gov Depressed Adolescents Respond Best to Combination Treatment - October 1. 2007 A combination of psychotherapy and antidepressant medication appears to be the most effective treatment for adolescents with study depressive disorder — more than medication alone or psychotherapy alone according to results from a major clinical trial funded by the National Institutes of Health’s National initiate of Mental Health (NIMH). The study was published in the October 2007 issue of the “Archives of General Psychiatry”. Source: www nih gov Folic Acid May Prevent Cleft Lip and Palate A new chew over finds that women who act folic acid supplements early in their pregnancy can substantially reduce their baby s chances of being born with a facial cleft. Source: www niehs nih gov Low Maternal Cholesterol Tied to Premature Birth - October 1. 2007 Pregnant women who have very low cholesterol may face a greater risk of delivering their babies prematurely than women with more discuss cholesterol levels a team led by the National Human Genome investigate Institute (NHGRI) part of the National Institutes of Health (NIH) reported today. obtain: www nih gov FDA has asked Genentech the manufacturer of Xolair (omalizumab) to add a new boxed warning to the drug’s labeling. This warning ordain emphasize that the product can cause anaphylaxis sometimes with delayed onset. Xolair administered subcutane… The Centers for Disease Control and Prevention (CDC) today released a inform that finds a wide be of variation in the prevalence of coronary heart disease (a narrowing of the arteries that cater the heart) heart attack and angina (chest pain that occurs when the heart does not get enough blood). The report provides the first ever information on the percentage of people living with heart disease… The Centers for Disease hold back and Prevention (CDC) in collaboration with a coalition of national partners is launching a new phase of the “hit the books the Signs. Act Early”… This warn is being issued based on information the agency received showing that 24 apparently related Web sites may be involved in the distribution of counterfeit prescription drugs. The Informed Decision Toolbox contains information about evidence-based management strategies. This training schedule is designed to inform pharmacists to the problem of low health literacy in patient populations and to identify the implications of this problem for the delivery of health care services. The AHRQ Preventable Hospitalization Costs (PHC) is a software schedule that 1) maps selected AHRQ Quality Indicators (QIs) for a state by county and 2) estimates the be savings associated with reducing the level of potentially avoidable hospitalizations. This pharmacy health literacy tool was designed to capture perspectives of three critical audiences-objective auditors pharmacy staff and patients. The three parts of the assessment are complementary and designed to create a comprehensive assessment. The goal of the be initiative is to measurably decrease the be of discrepant medication orders and the associated potential and actual patient injure. This toolkit is designed to assist all types of organizations whether caring for inpatients or outpatients or using an electronic medical record a paper-based system or both.

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"Comparison of ADHD treatments" posted by ~Ray
Posted on 2007-12-09 15:16:24

Initial advantages of medication management alone or in combination with behavioral treatment over purely behavioral or routine community compassionate waned in the years after 14 months of controlled treatment ended. However. Peter Jensen. M. D.. Columbia University and colleagues emphasized that “it would be incorrect to cerebrate from these results that treatment makes no difference or is not worth pursuing.” Their report is among four on the outcome of the MTA chew over published in the August. 2007 Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP). After three years. 45-71 percent of the youth in the original treatment groups were taking medication. However continuing medication treatment was no longer associated with exceed outcomes by the third year. “Our results suggest that medication can make a long-term difference for some children if it’s continued with optimal intensity and not started or added too late in a child’s clinical cover,” added Jensen. For the followup chew over a multi-site investigate team evaluated at ages 10-13. 485 children from the original MTA study the first major randomized trial comparing different treatments for ADHD published in l999. That chew over open that intensive medication management alone or in combination with behavioral therapy produced better outcomes than just behavioral therapy or usual community care. Ratings from families and teachers favored the combination treatment which allowed for somewhat lower medication doses. Also the careful management of medication by MTA physicians produced better outcomes than medication provided through usual community care sources. To understand why the initial advantage of medication wore off the researchers examined medication use patterns that emerged after formal treatment in the study ended. They found that children who had been assigned to intensive behavioral treatment were more likely to begin taking medication while those who had been taking medication were more likely to stop. For example among children originally in the behavioral treatment assort the incidence of high medication use increased from 14 to 45 percent. In a secondary analysis of the data that searched for possible explanations for the findings in the same issue of the JAACAP researchers led by James Swanson. Ph. D.. University of California at Irvine reported finding substantial individual variability in responses to medication. They identified three groups of children with different patterns of response. One group about a third of the children showed a gradual moderate improvement; a back up assort about half of the children showed larger initial improvement which was sustained through the third year; a third assort about 14 percent of the children responded well initially but then deteriorated as symptoms returned during the back up and third years. Swanson and colleagues suggested “trial withdrawals” for some children to determine if they still need to act medications. Another report by Swanson and colleagues in the same issue of the JAACAP confirmed an earlier finding from the MTA study that taking medication slowed growth. A group of 65 children with ADHD who had never taken medication grew somewhat larger about three-fourths of an inch and 6 pounds more on average than a assort of 88 peers who stayed on medication over the three years. Growth rates normalized for the children on medication by the third year but they had not made up for the earlier slowing in growth. In a fourth bind. Brooke Molina. Ph. D.. University of Pittsburgh and colleagues reported that despite treatment the children with ADHD showed significantly higher-than-normal rates of delinquency (27.1 percent vs. 7.4 percent) and substance use (17.4 percent vs. 7.8 percent) after three years. Earlier bear witness of lower substance use rates among children who had received intensive behavioral therapy had lessened by the third year. “These findings underscore the point that ADHD treatment for one year does not prevent serious problems from emerging later,” noted Molina.

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"Prevention of Osteoporosis through Vitamin Supplementation, Diet ..." posted by ~Ray
Posted on 2007-11-29 19:43:12

is a medical instruct where the bones become fragile and brittle overtime. Every hit the books throughout the be can be affected by osteoporosis. However based on the clinical evidence this instruct most likely affects the spine hip and wrist. According to some medical institutions women are four times more likely to create this condition over the course of their life compared to men. This figure does not indicate that men are not prone to developing osteoporosis but rather suggests that they are at less risk relative to women. Osteoporosis is age-related disease that affects most populate in later stages of the life. Classic signs and symptoms of osteoporosis are weakening of the strength and rigidity of particular axial and appendicular bones. Many doctors are concerned about the increased assay of fracture for their patients that suffered from this instruct. Since osteoporosis weakens the strength and rigidity of bones many doctors are concerned about increased assay of fracture for their patients. According the as many as half of all women and a accommodate of men older than 50 ordain end a hit the books due to osteoporosis. Osteoporosis is a silent disease which is usually overlooked until a bone is broken due to osteoporosis’ degradation and weakening cause. The troubling aspect of this disease is that symptoms are only felt in the later stages of its development which include loss of height due to weakening spine bone tenderness and hurt leg cramping particularly at night neck pain and discomfort. People who are affected by this condition undergo reduced bone mineral density (BMD) which measures the amount of minerals (such as calcium) open in your bones through special X-rays or other radiological images. Through the normal aging process our bones lose calcium and other minerals causing the bones to become more porous and weaker. The common bone condition is called osteopenia. People that generally undergo thicker bones and less degradation ordain minimize their risk for developing osteoporosis through this correlation is not definitive. Early detection is very important to involved the long term consequences of this silent disease. According to various experts osteoporosis is a preventable disease is a certain regiment lifestyle is followed. This lifestyle should consist of proper vitamin supplementation diet and exercise. Each of these factors affect and decrease the development of osteoporosis. For those that suffering with instruct for an extended period of time it has been observed that osteoporosis can be treated with and various other medical treatments. For those that would desire to preventative and reduce their risk of developing osteoporosis they look into altering the above mentioned factors. Since osteoporosis is a genetically linked disease caused by the alteration of 30 genes causing physiological deficiencies these lifestyle changes will not definitely cure those with instruct. It is highly advised that you ask with a reputable orthopedic surgeon or family practitioner to evaluate possible options. As previously mentioned our bones overtime suffer minerals especially calcium. populate in general particularly elderly women should consider 1200 to 1500 mg of calcium through or dietary take. A good obtain of calcium is low-fat milk which contains approximately 300 mg of calcium for an 8 oz glass of draw. Also. 1200 mg is ideal to prevent about condition called brittle hit the books disease. Currently some nutritionists accept that milk and other daily products cause acidification which draws calcium away from the system minimizing its utility of the rebuilding of bone. It has been suggested the nuts and vegetables are a better source of calcium. Also it accept that excess caffeine consumption can lead to the stripping of calcium from particular bones. One of the biggest components of calcium beneficial aid is an accompanying process of Vitamin D. Vitamin D plays a crucial role in calcium absorption which accept calcium to be deposited into weakening bones. Most people are unaware but Vitamin D is a unique vitamin is that our body uses UV rays to convert precursor compounds in Vitamin D3. To learn more about sources of Vitamin D please analyse my exclusive. Calcium and Vitamin D bring home the bacon together in a synergistic manner to back up strong rigid bones. One thing to keep in mind is that if calcium intake is limited or if there is malabsorption of calcium bone tissue will generally weaken. it is recommended that minimum doses of 1200 mg of calcium and 800 IU of Vitamin D for the best therapeutic cause. Based on these results it was observed that this theurapeutic combination significantly change magnitude the fracture of risk of elderly patients who received this treatment versus placebo recipients. It has been observed that Vitamin D helps the decrease abuse evaluate by 25% according to recent studies. Vitamin D supplementation also helps minimize bone abuse by improving muscle function and stability. It is observed that Vitamin D deficiency can strongly alter to go across weakness which get elderly patient more prone to severe falls or bone injuries. There are many various studies that have indicated that excessive protein intake can increase urinary calcium loss which ultimately minimize the available calcium to be absorbed. Overtime this long call deficiency can increase the assay of abuse from affected individuals. I can across a great questionnaire from the National Osteoporosis Foundation to back up determined you level of assay for this instruct: Exercise is a strong component that doctors’ urge their patients to go. Exercise done in moderation helps alter and build the bones throughout the body. It increase calcium regeneration rates so that bones are rebuilt on a regular basis. Here are some very helpful apply regiments presented by the National Osteoporosis Foundation. If you follow this cerebrate you ordain hit the books some very helpful exercise moves and explaination to reduce and minimize risk of osteoporosis. Even possibly change the signs and symptoms of this disease. Osteoporosis is a widespread disease that affects millions of people per year. Unfortunately it is hard to sight until the later stages due to minimal symptoms experienced. Most people should therefore by proactive and go certain health regiments. Eat healthy add your be with quality vitamins and alter your muscles and bones for the longevity of your health. Sometimes we can not avoid developing a certain instruct but we can definitely try and overcome it through active effort. The information provided on this place is intended for your general knowledge only. It is not a substitute for professional medical advice or treatment for specific medical conditions. Always desire advice of your physician or other qualified health compassionate provider with any questions you may have regarding a pre-existing medical condition. The information on this website is not intended to analyse treat aid or prevent any disease. Never disregard medical advice or decelerate seeking it because of something you undergo read on Doc1Vitamins com site.

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"Postdoc: Cartilage MRI / MRS" posted by ~Ray
Posted on 2007-11-19 14:26:41

A postdoctoral position is available in the Nuclear Magnetic Resonance Unit (Richard Spencer. Chief) of the National Institute on Aging of the National Institutes of Health located in Baltimore. Maryland. The work will center on spectroscopic and imaging studies of cartilage create from raw material derived from tissue engineering protocols and from animals. Other research opportunities may be available depending upon the interests and accent of the successful candidate. MRI instrumentation consists of a triple-resonance vertical wide-bore Bruker DMX 400 Avance system with microimaging and solids capability a double-resonance Bruker 7T/30 cm DBX system and a double-resonance Bruker ABX 1.9T/31 cm Biospec. In addition a 3T whole-body system is expected to be installed by early 2008. A background in MRI imaging or NMR spectroscopy of connective create from raw material is preferred although applicants with expertise in cartilage biology who have the desire to learn MRI techniques are also strongly encouraged to apply. We also arouse applications from individuals with undergo in other areas of biological MRI and NMR. The appointment ordain be as an IRTA Postdoctoral Fellow for U. S citizens or as a Visiting Fellow for non-citizens. Accordingly applicants must undergo fewer than five years of postdoctoral experience. Interested individuals should click on the button below or e-mail their CV and the names telephone numbers and e-mail addresses of at least three references to:Dr. Richard SpencerNMR Unit. NIH/NIAGRC 4D-065600 Nathan Shock DriveBaltimore. MD 21224Tel.: (410) 558-8226telecommunicate: Web site: The NIH is dedicated to building a diverse community in its training and employment programs. Please note: There is a limit on the number of postdoctoral fellowship applications one may submit through the NIH site. Individuals may submit up to ten (10) applications per 12-month period. Each application one submits counts toward his/her total; there is no way to "retract" an application once it is submitted. For these reasons the NIH Office of Intramural Training and Education (OITE) urges each would-be applicant to be discriminating when choosing to bear on for a fellowship. air information and communicate with the public and interested groups on health and investigate advances and on new directions for investigate.

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Related article:
http://jobs.phds.org/job/5910/national-institute-on/postdoc-cartilage-mri

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"Heart disease risk higher if a brother or sister has heart problems" posted by ~Ray
Posted on 2007-11-11 16:11:54

The long running Framingham Heart Study was conducted by the National Heart. Lung and daub initiate (NHLBI) which is a move of the National Institutes of Health (NIH). The study has revealed that middle-aged individuals have as much as a 45 percent risk of having a cardiovascular event such as a heart attack stroke or peripheral artery disease if a brother or sister has had such an event. The researchers say that change surface when adjustments were made for the fact that siblings may have similar lifestyle-related risk factors and may be of similar ages the assay associated with having a sibling with cardiovascular disease remained high. As a command doctors will cause the relative assay for cardiovascular disease by evaluating known risk factors such as family history of heart disease age high blood pressure high cholesterol overweight smoking physical inactivity and diabetes. While many experts undergo suspected in the past that having a parent or sibling with heart disease increases the assay this chew over shows quite clearly that having a sibling with heart disease is a significant assay factor independent of other measures. NHLBI Director Dr. Elizabeth G. Nabel says the chew over illustrates that even people who are not at high risk based on their own health status should talk to their doctors about the history of heart disease in their families among siblings as come up as parents and ask what they can do to prevent a heart contend or touch. In the chew over the researchers evaluated siblings from among 1188 men and 1287 women all were participants in the Framingham Heart Study. All were at least 30 years old at the measure of a baseline examination and were followed for eight years for the occurrence of a cardiovascular disease event. The chew over’s bring about compose Joanne Murabito. MD. ScM of Boston University says they determined that the assay from a sibling with a cardiovascular disease event remained elevated change surface after taking into be age and other assay factors that may assemble within families. She suggests that assay may be even higher than the assay related to having a parent with cardiovascular disease and is significant even in persons with borderline elevated levels of total cholesterol when doctors are often undecided about medication treatment. Unlike other studies of family history the Framingham chew over is one of the first studies to take an independent unbiased look at sibling assay. Dr. Murabito says the findings suggest that taking an accurate family history should be a crucial part of every physician’s method of assessing heart disease assay and should go beyond a simple ‘yes’ or ‘no’ challenge about the presence of disease in the family. Murabito believes patients should alter an effort to collect medical history information from their siblings and parents and alter sure to inform their siblings if they have a cardiovascular disease event such as a heart contend or stroke. She also believes that the reasons behind the strong association of risk between siblings are environmental as come up as genetic and as come up as sharing the same genetic makeup siblings may overlap similar dietary habits and physical activity patterns established in their early years while living in the same household which may continue on into adulthood when genetic factors begin to manifest. Christopher O’Donnell. MD. MPH associate director of NHLBI’s Framingham Heart Study and the chew over senior compose says that while family history cannot be controlled there are many things which can be done to hold back the assay for heart disease such as keeping your blood compel cholesterol and blood dulcify under hold back maintaining a healthy weight avoiding smoking and getting regular physical activity.

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Related article:
http://google-sina.com/2007/11/03/heart-disease-risk-higher-if-a-brother-or-sister-has-heart-problems/

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